A mineral systems analysis for Cu-Mo-Au in the Delamerian Orogen has been conducted to assess the orogen's potential for containing this type of mineral occurrence. A conceptual model was delineated, and prospectivity maps were created. These maps can serve partially for drill and sampling campaign targeting. The conceptual model is implemented as a flexible workflow in ArcGIS, and it can be readily updated with new data. It is based on fuzzy logic manipulation of classified mineral system - critical data components prepared as evidence layers in GIS, to present various component statistical probability scenarios in map format for evaluation. Several of the critical elements of the conceptual model will be reassessed when more detailed geochemical, mineralogical, petrophysical, and structural data become available after the conclusion of the currently underway MinEx NDI drilling campaign. For example, the fractionation and oxidation state of the mapped igneous intrusive/volcanic bodies will then be better estimated by making direct measurements and performing new sampling of the geochemical properties of rocks from the drill chips and drill core, or from surface mapping. Similarly, the conduct of numerical simulation and 3D geological modelling will confirm or disprove the proposed model, which supports the role of structures that traverse most of the lithospheric crust. A matter of primary interest for the NDI basement drill sampling campaign as it unfolds should be to obtain direct information concerning the extent and nature of the interpreted Mount Wright Volcanics and other contemporaneous igneous intrusive and volcanic suites related to the Delamerian island arc or back-arc crustal development. Later on, studies can be further focused on zones that are traversed by the interpreted crustal-scale discontinuities.