The Mount Painter basement igneous complex is dominated by granite intrusions and volcanic rocks, most of which are fractionated and have a high uranium content. Apart from Mount Painter itself, where uranium was mined more than 60 years ago, there has been no hard rock uranium mining in the region. The sand-hosted secondary uranium mineralisation within Tertiary sediments at the Beverley deposit located east-north-east of Mount Painter is clearly derived from the complex. Data presently available on the granites of the complex was re-examined to ascertain whether any particular unit has been responsible for the sedimentary deposits and whether any particular granites may host or give rise to, economic primary (hard rock) deposits. It was observed from studying the data that granites north and south of the Paralana Fault are different. There is a southern petrological province dominated by Mount Neill Granite and related volcanic rocks (the Mount Neill Supersuite) that has K2O/Na2O near 1, high total alkalis, high oxidation state and an age around 1575 Ma, and a separate northern province dominated by granites with high K2O/Na2O, a reduced oxidation state and with an age near 1556 Ma. The Paralana Fault separating the provinces is considered to be a major crustal structure. The provinces represent two juxtaposed basement terranes defined by the compositions of their two sets of granitic rocks. Granites of both provinces have related volcanic facies, and hence they must have crystallised near the surface. This is significant because, generally, near-surface originating granites are those that are associated with mineralisation. The haematite breccias of Mount Painter are hydrothermal breccias produced by Mount Neill Granite at depth: there are only a few small exposures of Mount Neill Granite in this area. The Mount Neill Supersuite closely matches the suite of granites formed around Olympic Dam. The selected least altered sample has 20 ppm U, i.e. the same as the average OD value (21 ppm). The northern exposures of the Mount Neill Granite and the Pepegoona Rhyolite appear to be part of a caldera which has prospectivity for hosting Olympic Dam style haematite breccia mineralisation. The Yerila unit present on the southern side of the Mount Babbage block, in the north-eastern part of the Mount Painter Inlier, is not granite, although parts of its protolith may have been a deformed granite. The unit's enrichment in Th, U and REEs is metasomatic, producing allanite, monazite and even zircon. Whole rock geochemical and mineralogical data indicate that the enriched rocks are calcsilicates. All calcsilicate rocks in the complex, but especially in the high U + Th areas, should be more closely examined for skarn type economic mineral deposits. In the northern petrological province, the British Empire Granite is a highly fractionated, felsic and oxidised I-type granite with high U and high U/Th. It has similarities with the “alaskite” hosting the Rossing deposit in Namibia.