Punt Hill is the name given to a series of Cu–Au skarn prospects lying within the Olympic Cu–Au Province of the eastern Gawler Craton. Although highly prospective, exploration in the region is both expensive and technically challenging owing to hundreds of metres of post-mineralisation cover. The Geological Survey of South Australia, in collaboration with Monax Mining, used the Punt Hill region to develop a multidisciplinary approach for characterising, mapping and predicting alteration associated with skarn-hosted Cu–Au mineralisation. A particular focus was given to progressing the understanding of skarn development and generating exploration criteria and predictive models to aid future exploration in the region. Using magnetic and density modelling, plus determination of natural dispersion patterns of the trace metal antimony to identify kilometre-scale geochemical ‘footprints’, and by carrying out a semi-quantitative estimation of whole rock mineralogical assemblages' garnet to pyroxene ratio to provide an indication of proximity to the source of hydrothermal fluids, derived data were found to support a mineralisation model where magmatic–hydrothermal fluids sourced from deep-seated Hiltaba Suite intrusions moved up NW–SE-trending faults in a generally northward direction and dispersed into calcareous strata, forming prograde skarn assemblages. At a later time the presence of either cooled and evolved fluids, or a separate shallowly sourced fluid, resulted in retrograde alteration and Cu–Au ± Ag–Zn–Pb mineralisation. Datasets have been incorporated into a 3D Gocad model which serves as a mineral potential map that displays components of mineral systems developed in the Punt Hill region down to ~5 km depth.