Commercial hydrocarbon discoveries in the Otway Basin are currently limited to the Victorian Port Campbell Embayment, both onshore and offshore and the onshore Penola Trough in South Australia. Previous AFTA®-based studies have shown that the regional thermal history is a key factor controlling the distribution of these discoveries, the results of these studies providing a viable means of focussing exploration in the “thermally” most favourable regions of the basin. In simple terms, thermally favourable regions are those in which the negative effects of elevated mid-Cretaceous heat-flow have been overcome by sufficiently thick Late Cretaceous and Tertiary burial to re-start hydrocarbon generation from Early Cretaceous source rocks. The offshore Port Campbell Embayment is such a favourable region but local structural complexity in this relatively small area provide significant challenges for predicting the location of additional hydrocarbon accumulations. Available open file organic maturity information from offshore wells (vitrinite reflectance, spore colour (TAI), Tmax) suggests kilometre-scale uplift and erosion events in the area, but the timing of these events is very poorly constrained by the current data distribution. Similarly, seismic sections clearly show a number of post-early Cretaceous structuring episodes, but even the relative importance of these episodes on the generation and preservation of hydrocarbons is unconstrained....